Name the factor that effect the binding of O2 to haemoglobin to form oxyhaemoglobin in the tissue
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Name the factor that effect the binding of O2 to haemoglobin to form oxyhaemoglobin in the tissue
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Answer:
Factors that Affect Hemoglobin Dissociation Curve
There are several important factors that affect the affinity of hemoglobin to oxygen as therefore affect the oxygen-hemoglobin dissociation curve. These factors include the (1) pH (2) temperature (3) carbon dioxide (4) 2,3-BPG and (5) carbon monoxide. By increasing the hydrogen ion concentration (and therefore the pH), the temperature, the carbon dioxide concentration or the amount of 2,3-BPG present in the red blood cell, we ultimately decrease the affinity of hemoglobin to oxygen and therefore shift the curve to the right side. This allows us to unload more oxygen to our tissues. On the other hand, by increasing the concentration of carbon monoxide, we actually increase the affinity of hemoglobin for oxygen and we therefore shift the curve to the left side. This means that less oxygen will actually be delivered to our tissues.